Conclusion the movement of macromolecules like proteins and polysaccharides into or out of the cell is known as bulk transport. Park jh 2014 endocytosis and exocytosis of nanoparticles in mammalian cells. Learn biology endocytosis exocytosis cells with free interactive flashcards. Endocytosis and exocytosis of nanoparticles in mammalian cells. Choose from 453 different sets of biology endocytosis exocytosis cells flashcards on quizlet. The exocytosis of mesoporous silica nanoparticles msns from mammalian cells is demonstrated for the first time. Endocytosis and exocytosis involve processes of complex vesicular systems, which. Exocytosis of peptide functionalized gold nanoparticles in. Nanoparticles exit the cell via three types of pathway.
Ligand modified nanoparticles increases cell uptake, alters endocytosis and elevates glioma distribution and internalization. Ligand modified nanoparticles increases cell uptake. Endocytosis, intracellular fate, accumulation, and agglomeration of. Exocytosis of mesoporous silica nanoparticles from. Endocytosis and exocytosis of nanoparticles in mammalian cells nuri oh,1,2 ji ho park1department of bio and brain engineering. Nanoparticles enter the cell via four types of pathway.
Vesicular transport plays an important role in the distribution of synthesized proteins and their delivery to various compartments of the cell. Dovepress dovepress 53 endocytosis and exocytosis of nanoparticles in mammalian cells therefore. Exocytosis of peptide functionalized gold nanoparticles in endothelial cells. The differences in the degree of exocytosis of msns between healthy and cancer cells are shown to be responsible for the asymmetric transfer of the particles between both cell types. Endocytosis and exocytosis of nanoparticles in mammalian cells ijn. Most of the nanoparticles are first coated with the serum proteins and then met with the plasma membrane of cells. Schematic of endocytosis and exocytosis patterns of nanoparticles.
Recent findings suggest that the extracellular calcium concentration can influence the release of nps from cells. In particular, exocytosis is of significance in the removal of nanoparticles with drugs and contrast agents from the body, while endocytosis is of great importance for the targeting of nanoparticles in disease sites. Endocytosis and exocytosis of nanoparticles in mammalian cells nuri oh,1,2 jiho park1department of bio and brain engineering. Molecular mechanism and physiological functions of. Engineered nanoparticles that can be injected into the human body hold tremendous potential to detect and treat complex diseases. When we study the endocytosis and exocytosis of nanoparticles, cells are treated with the nanoparticles in the culture medium containing various serum proteins.
581 336 383 73 264 132 1244 958 34 62 694 1342 455 203 808 1063 430 837 1285 742 123 843 155 1108 1368 180 1076 960 1386 1056 934 161 1458 939 832 458 1200 54